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NR4A1 Produits

(Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Catégories

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].

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Catégories NR4A1 en vedette

NR4A1 Anticorps

High quality antibodies with extensive validation data.

NR4A1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NR4A1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NR4A1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (5)
N° du produit ABIN2777511
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (3)
N° du produit ABIN6144826
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7180055
Quantité 100 μL
Fiche technique Fiche technique

NR4A1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958267
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381367
Quantité 96 tests
Fiche technique Fiche technique

NR4A1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312979
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312981
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3084690
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NR4A1

Qin, Gao, Wang, Huang, Peng, Mo, Wang: "Nur77 promotes cigarette smoke‑induced autophagic cell death by increasing the dissociation of Bcl2 from Beclin-1." dans: International journal of molecular medicine, Vol. 44, Issue 1, pp. 25-36, (2019) (PubMed).

Li, Yin, Hong, Liu, Jin, Wang, Wang, Tian: "The orphan nuclear receptor NUR77 promotes trophoblast invasion at early pregnancy through paracrine placental growth factor." dans: Journal of molecular medicine (Berlin, Germany), Vol. 97, Issue 9, pp. 1359-1373, (2019) (PubMed).

Qi, Guo, Wei, Jin, Wang, Mao: "The involvement of NR4A1 and NR4A2 in the regulation of the luteal function in rats." dans: Acta histochemica, Vol. 120, Issue 8, pp. 713-719, (2018) (PubMed).

Imura, Kobayashi, Suzutani, Ichikawa-Tomikawa, Chiba: "Differential expression of a stress-regulated gene Nr4a2 characterizes early- and late-born hippocampal granule cells." dans: Hippocampus, (2018) (PubMed).

Bian, Chen, Yang, Li, Zhang, Zhang, Wang, Zhao, Zhang, Chen, Zheng, Sun, Wang, Chien, Wu: "Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation." dans: Nature communications, Vol. 8, pp. 14420, (2017) (PubMed).

Geradts, Groth, Wu, Jin: "Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS)." dans: Breast cancer research and treatment, Vol. 157, Issue 3, pp. 447-59, (2017) (PubMed).

Hedrick, Lee, Safe: "The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists." dans: Molecular carcinogenesis, Vol. 56, Issue 9, pp. 2066-2075, (2017) (PubMed).

Li, Zhao, Xu, Shan, Hu, Qiu, Xu: "The autism-related gene SNRPN regulates cortical and spine development via controlling nuclear receptor Nr4a1." dans: Scientific reports, Vol. 6, pp. 29878, (2016) (PubMed).

Reynolds, Hancock, Ray, Kener, Draney, Garland, Hardman, Bikman, Tessem: "β-Cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion." dans: American journal of physiology. Endocrinology and metabolism, Vol. 311, Issue 1, pp. E186-201, (2016) (PubMed).

Nowakowski, Pollen, Sandoval-Espinosa, Kriegstein: "Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development." dans: Neuron, Vol. 91, Issue 6, pp. 1219-1227, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à NR4A1

nuclear receptor subfamily 4 group A member 1 (NR4A1), nuclear receptor subfamily 4, group A, member 1 (Nr4a1), Gfrp, GFRP1, Hbr-1, Hbr1, HMR, Hmr, N10, NAK-1, NGFI-B, Ngfi-b, NGFIB, NP10, NUR77, nur77, Nur77, TIS1, TR3

Protein level used designations for NR4A1

  • ST-59
  • TR3 orphan receptor
  • early response protein NAK1
  • growth factor-inducible nuclear protein N10
  • hormone receptor
  • nerve growth factor IB nuclear receptor variant 1
  • nuclear hormone receptor NUR/77
  • nuclear receptor subfamily 4 group A member 1
  • orphan nuclear receptor HMR
  • orphan nuclear receptor TR3
  • steroid receptor TR3
  • testicular receptor 3
  • orphan nuclear receptor NGFI-B
  • nuclear protein N10
  • Orphan nuclear receptor HMR
  • immediate early gene transcription factor NGFI-B
  • nerve growth factor induced protein I-B
  • nerve growth factor-induced protein I-B
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