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NR3C2 Produits

(Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

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Catégories NR3C2 en vedette

NR3C2 Anticorps

High quality antibodies with extensive validation data.

NR3C2 Kits ELISA

Reliable ELISA kits for a wide range of species.

NR3C2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NR3C2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN1681109
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Chicken, Human, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN396956
Quantité 50 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro), ICC
Validations
  • (3)
N° du produit ABIN7431818
Quantité 100 μL
Fiche technique Fiche technique

NR3C2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969024
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958266
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958265
Quantité 96 tests
Fiche technique Fiche technique

NR3C2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN2752870
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093765
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3136765
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NR3C2

Li, Tian, Wang, Hu, Qin, Xu, Liu, Hao, Tian: "LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." dans: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).

Leite-Dellova, Szriber, Merighe, Polidoro, Rebouças, Oliveira-Souza, de Mello-Aires: "Signaling pathways involved in the rapid biphasic effect of aldosterone on Na+/H+ exchanger in rat proximal tubule cells." dans: The Journal of steroid biochemistry and molecular biology, Vol. 182, pp. 87-94, (2018) (PubMed).

Qiao, He, Wei, Xia, Bao: "Effects of Hyriopsis cumingii Polysaccharides on Mice Immunologic Receptor, Transcription Factor, and Cytokine." dans: Journal of food science, Vol. 81, Issue 5, pp. H1288-94, (2016) (PubMed).

Liu, Jiang, Zhang, Li, Li, Xie, Hu: "Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." dans: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).

Rigiracciolo, Scarpelli, Lappano, Pisano, Santolla, Avino, De Marco, Bussolati, Maggiolini, De Francesco: "GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells." dans: Oncotarget, Vol. 7, Issue 1, pp. 94-111, (2016) (PubMed).

Ong, Chng, Meaney, Buschdorf: "Decreased hippocampal mineralocorticoid:glucocorticoid receptor ratio is associated with low birth weight in female cynomolgus macaque neonates." dans: Journal of molecular endocrinology, Vol. 51, Issue 1, pp. 59-67, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à NR3C2

nuclear receptor subfamily 3, group C, member 2 (nr3c2), nuclear receptor subfamily 3 group C member 2 (nr3c2), nuclear receptor subfamily 3 group C member 2 (NR3C2), mineralocorticoid receptor (LOC443144), nuclear receptor subfamily 3, group C, member 2 (Nr3c2), nuclear receptor subfamily 3, group C, member 2 (NR3C2), nuclear receptor subfamily 3 group C member 2 L homeolog (nr3c2.L), LOC443144, LOC100302443, MCR, MLR, Mlr, mlr, mr, MR, NR3C2, NR3C2VIT, si:ch211-189l17.1

Protein level used designations for NR3C2

  • mineralocorticoid receptor
  • nuclear receptor subfamily 3, group C, member 2
  • nuclear receptor subfamily 3 group C member 2
  • aldosterone receptor
  • mineralocorticoid receptor 1
  • mineralocorticoid receptor delta
  • MR
  • Mineralocorticoid receptor (aldosterone receptor)
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