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NSUN2 Produits

(NOP2/Sun Domain Family, Member 2 (NSUN2))

Catégories

This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011].

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Catégories NSUN2 en vedette

NSUN2 Anticorps

High quality antibodies with extensive validation data.

NSUN2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NSUN2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
N° du produit ABIN1681117
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7173496
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6263746
Quantité 100 μL
Fiche technique Fiche technique

NSUN2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231553
Quantité 96 tests
Fiche technique Fiche technique

NSUN2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3094279
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3134928
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2727652
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NSUN2

Blanco, Bandiera, Popis, Hussain, Lombard, Aleksic, Sajini, Tanna, Cortés-Garrido, Gkatza, Dietmann, Frye: "Stem cell function and stress response are controlled by protein synthesis." dans: Nature, Vol. 534, Issue 7607, pp. 335-40, (2016) (PubMed).

Chaumet, Wright, Seet, Tham, Gounko, Bard: "Nuclear envelope-associated endosomes deliver surface proteins to the nucleus." dans: Nature communications, Vol. 6, pp. 8218, (2015) (PubMed).

Lv, Liu, Cheng, Yu, Xiong, Hu, Tang, Zeng, Sang: "SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer." dans: Scientific reports, Vol. 5, pp. 17940, (2015) (PubMed).

Hussain, Tuorto, Menon, Blanco, Cox, Flores, Watt, Kudo, Lyko, Frye: "The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation." dans: Molecular and cellular biology, Vol. 33, Issue 8, pp. 1561-70, (2013) (PubMed).

Horn, Kim, Wright, Wong, Stewart, Burke, Roux: "A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton." dans: The Journal of cell biology, Vol. 202, Issue 7, pp. 1023-39, (2013) (PubMed).

Alsarraj, Faraji, Geiger, Mattaini, Williams, Wu, Ha, Merlino, Walker, Bosley, Xiao, Andresson, Esposito, Smithers, Lugo, Prinjha, Day, Crawford, Ozato, Gardner, Hunter: "BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80746, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Khan, Rafiq, Noor, Hussain, Flores, Rupp, Vincent, Malli, Ali, Khan, Ishak, Doherty, Weksberg, Ayub, Windpassinger, Ibrahim, Frye, Ansar, Vincent: "Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability." dans: American journal of human genetics, Vol. 90, Issue 5, pp. 856-63, (2012) (PubMed).

Blanco, Kurowski, Nichols, Watt, Benitah, Frye: "The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate." dans: PLoS genetics, Vol. 7, Issue 12, pp. e1002403, (2011) (PubMed).

Gudise, Figueroa, Lindberg, Larsson, Hallberg: "Samp1 is functionally associated with the LINC complex and A-type lamina networks." dans: Journal of cell science, Vol. 124, Issue Pt 12, pp. 2077-85, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à NSUN2

NOL1/NOP2/Sun domain family member 2 (Nsun2), NOP2/Sun RNA methyltransferase family member 2 (NSUN2), NOP2/Sun RNA methyltransferase family, member 2 (Nsun2), NOP2/Sun RNA methyltransferase family member 2 S homeolog (nsun2.S), D13Wsu123e, Misu, MISU, MRT5, RGD1311954, SAKI, TRM4

Protein level used designations for NSUN2

  • Myc-induced SUN domain containing protein
  • NOL1/NOP2/Sun domain family 2
  • myc-induced SUN domain-containing protein
  • tRNA (cytosine(34)-C(5))-methyltransferase
  • tRNA (cytosine-5-)-methyltransferase NSUN2
  • NOL1/NOP2/Sun domain family, member 2
  • NOP2/Sun domain family, member 2
  • 5-methycytoisine methyltransferase
  • Myc-induced SUN-domain-containing protein
  • NOL1/NOP2/Sun domain family member 2
  • hTrm4
  • substrate of AIM1/Aurora kinase B
  • tRNA methyltransferase 4 homolog
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