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NTRK3 Produits

(Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Catégories

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].

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Catégories NTRK3 en vedette

NTRK3 Anticorps

High quality antibodies with extensive validation data.

NTRK3 Kits ELISA

Reliable ELISA kits for a wide range of species.

NTRK3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NTRK3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (6)
N° du produit ABIN7443641
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p), IF, ICC
Validations
  • (11)
N° du produit ABIN1499842
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (5)
N° du produit ABIN2784511
Quantité 100 μL
Fiche technique Fiche technique

NTRK3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968903
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116172
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
N° du produit ABIN5692236
Quantité 96 tests
Fiche technique Fiche technique

NTRK3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5570035
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5569488
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313121
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NTRK3

Gómez-Pineda, Torres-Cruz, Vivar-Cortés, Hernández-Echeagaray: "Neurotrophin-3 restores synaptic plasticity in the striatum of a mouse model of Huntington's disease." dans: CNS neuroscience & therapeutics, Vol. 24, Issue 4, pp. 353-363, (2018) (PubMed).

Yang, Massa, Tran, Simmons, Rajadas, Zeng, Jang, Carsanaro, Longo: "A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth." dans: Neuropharmacology, Vol. 110, Issue Pt A, pp. 343-61, (2016) (PubMed).

Chung, Chung, Lee, Chung, Yang, Lee, Choi, Chang, Kim, Suh, Lee, Hwang, Do, Kim: "Expression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats." dans: Journal of veterinary science, Vol. 17, Issue 1, pp. 97-102, (2016) (PubMed).

Lawn, Krishna, Pisklakova, Qu, Fenstermacher, Fournier, Vrionis, Tran, Chan, Kenchappa, Forsyth: "Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells." dans: The Journal of biological chemistry, Vol. 290, Issue 6, pp. 3814-24, (2015) (PubMed).

Maury, Côme, Piskorowski, Salah-Mohellibi, Chevaleyre, Peschanski, Martinat, Nedelec: "Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes." dans: Nature biotechnology, Vol. 33, Issue 1, pp. 89-96, (2015) (PubMed).

Rezaee, Rellick, Piedimonte, Akers, OLeary, Martin, Craig, Gibson: "Neurotrophins regulate bone marrow stromal cell IL-6 expression through the MAPK pathway." dans: PLoS ONE, Vol. 5, Issue 3, pp. e9690, (2010) (PubMed).

Delcroix, Curtis, Schiller, Montero-Menei: "EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells." dans: Differentiation; research in biological diversity, Vol. 80, Issue 4-5, pp. 213-27, (2010) (PubMed).

Huang, Lai, Wu, Hsu, Cheng, Lan, Chiu: "BDNF mediated TrkB activation is a survival signal for transitional cell carcinoma cells." dans: International journal of oncology, Vol. 36, Issue 6, pp. 1469-76, (2010) (PubMed).

Huang, Lai, Wu, Cheng, Chiu: "TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells." dans: International journal of oncology, Vol. 37, Issue 4, pp. 943-9, (2010) (PubMed).

Esteban, Yoon, Becker, Dorsey, Caprari, Palko, Coppola, Saragovi, Randazzo, Tessarollo: "A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin." dans: The Journal of cell biology, Vol. 173, Issue 2, pp. 291-9, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à NTRK3

neurotrophic receptor tyrosine kinase 3 (NTRK3), neurotrophic receptor tyrosine kinase 3 (Ntrk3), neurotrophic tyrosine kinase, receptor, type 3 (Ntrk3), AW125844, gp145(trkC), Ntrk3_tv3, TRKC, trkC, TrkC

Protein level used designations for NTRK3

  • ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
  • ETV6-NTRK3 fusion
  • GP145-TrkC
  • NT-3 growth factor receptor
  • tyrosine kinase receptor C
  • neural receptor protein-tyrosine kinase (trkC)
  • trk-C
  • trkC tyrosine kinase
  • neurotrophin-3
  • neurotrophic tyrosine kinase receptor type 3
  • tyrosine kinase C receptor, TrkC receptor, high-affinity neurotrophin receptor
  • gp145-trkC
  • neurotrophic tyrosine kinase, receptor, type 3
  • NT-3 growth factor receptor-like
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