NUB1 Produits
(Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
Catégories
This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
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Catégories NUB1 en vedette
NUB1 Anticorps
High quality antibodies with extensive validation data.
NUB1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NUB1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IHC (p), IF, FACS
Validations
- (7)
N° du produit
ABIN1490743
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
N° du produit
ABIN389078
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
N° du produit
ABIN6263785
Quantité
100 μL
Fiche technique
Fiche technique
NUB1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381369
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Cow
Analytical Method
Validations
N° du produit
ABIN1144444
Quantité
96 tests
Fiche technique
Fiche technique
NUB1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313137
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313139
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3119810
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits NUB1
: "Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L." dans: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32905-13, (2003) (PubMed).: "The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1." dans: Human molecular genetics, Vol. 11, Issue 22, pp. 2723-33, (2002) (PubMed).
: "NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression." dans: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20603-9, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à NUB1
negative regulator of ubiquitin-like proteins 1 (Nub1), negative regulator of ubiquitin like proteins 1 (NUB1), 4931404D21Rik, 6330412F12Rik, BS4, NUB1L, NY-REN-18, NYREN18Protein level used designations for NUB1
- NEDD8 ultimate buster 1
- NEDD8 ultimate buster-1
- NY-REN-18 antigen
- renal carcinoma antigen NY-REN-18
- Nedd8 ultimate buster-1
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- Nucleaoside Diphosphate Kinase
- Nuclear Antigen
- Nuclear Casein Kinase and Cyclin-Dependent Kinase Substrate 1
- Nuclear Factor 1
- Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha
- Nuclear LaMiN Family Member (Lmn-1)
- Nuclear Marker
- Nuclear Matrix Protein 22
- Nuclear Receptor Subfamily 1, Group D, Member 2
- Nuclear Receptor Subfamily 1, Group H, Member 2/3
- Nuclear Receptor Subfamily 2, Group C, Member 1
- Nuclear Transcription Factor Y, beta
- Nuclease
- Nuclease P1
- Nuclease S1
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