OAS1 Produits
(2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
Catégories
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories OAS1 en vedette
OAS1 Anticorps
High quality antibodies with extensive validation data.
OAS1 Kits ELISA
Reliable ELISA kits for a wide range of species.
OAS1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
OAS1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7435079
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7435082
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (7)
- (3)
N° du produit
ABIN390164
Quantité
400 μL
Fiche technique
Fiche technique
OAS1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5593383
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Pig
Analytical Method
Validations
N° du produit
ABIN1118759
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5651267
Quantité
96 tests
Fiche technique
Fiche technique
OAS1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1313295
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121603
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313297
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits OAS1
: "Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells." dans: Immunology and cell biology, Vol. 92, Issue 2, pp. 105-15, (2014) (PubMed).: "RIG-I-like receptors mediate innate antiviral response in mouse testis." dans: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1455-67, (2013) (PubMed).
: "The association of elevated 2',5'-oligoadenylate-dependent RNase L with lung cancer correlated with deficient enzymatic activity and decreased capacity of RNase L dimerization." dans: Lung cancer (Amsterdam, Netherlands), Vol. 78, Issue 1, pp. 30-8, (2012) (PubMed).
: "Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway." dans: Cancer research, Vol. 71, Issue 1, pp. 255-65, (2011) (PubMed).
: "Azithromycin induces anti-viral responses in bronchial epithelial cells." dans: The European respiratory journal, Vol. 36, Issue 3, pp. 646-54, (2010) (PubMed).
: "The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo." dans: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28343-51, (2009) (PubMed).
: "Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression." dans: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15845-52, (2008) (PubMed).
: "IFI16 in human prostate cancer." dans: Molecular cancer research : MCR, Vol. 5, Issue 3, pp. 251-9, (2007) (PubMed).
: "A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L." dans: Journal of virology, Vol. 81, Issue 11, pp. 5561-72, (2007) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à OAS1
2',5'-oligoadenylate synthetase 1 (OAS1), 2'-5'-oligoadenylate synthetase 1 (OAS1), 2'-5' oligoadenylate synthetase 1A (Oas1a), protein phosphatase 2 catalytic subunit beta (Ppp2cb), 2'-5'-oligoadenylate synthetase 1 (Oas1), IFI-4, L3, OAS1, OIAS, OIASI, Pp2a2Protein level used designations for OAS1
- 2',5'-oligoadenylate synthetase 1
- 2',5'-oligoadenylate synthetase 1, 40/46kDa
- 2'-5'-oligoadenylate synthase 1
- (2-5')oligo(A) synthase 1
- (2-5')oligo(A) synthetase 1
- 2'-5' oligoadenylate synthetase
- 2-5A synthase 1
- 2-5A synthetase 1
- p42 OAS
- 2-5-oligoadenylate synthetase 1
- 2'-5' oligoadenylate synthetase 1
- 2',5'-oligo A synthetase 1
- 2'-5' oligoadenylate synthetase 1 p48 isoform
- 2'-5' oligoadenylate synthetase 1 p52 isoform
- 2'-5'-oligoisoadenylate synthetase 1
- E18/E16
- p46/p42 OAS
- 2'-5'-oligoadenylate synthetase 1-like
- 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- (2-5')oligo(A) synthase 1A
- (2-5')oligo(A) synthetase 1A
- 2'-5'-oligoadenylate synthase 1A
- 2-5A synthase 1A
- 2-5A synthetase 1A
- PP2A-beta
- protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
- protein phosphatase 2, catalytic subunit, beta isoform
- protein phosphatase 2A catalytic alpha subunit
- protein phosphatase 2a, catalytic subunit, beta isoform
- protein phosphatase-2A-beta
- serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 1
Vous êtes ici:
