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OPA1 Produits

(Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Catégories

This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Catégories OPA1 en vedette

OPA1 Anticorps

High quality antibodies with extensive validation data.

OPA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

OPA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (6)
N° du produit ABIN6145031
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (6)
N° du produit ABIN2565745
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN3043457
Quantité 100 μg
Fiche technique Fiche technique

OPA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Sandwich ELISA
Validations
N° du produit ABIN419938
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN427337
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Sandwich ELISA
Validations
N° du produit ABIN434335
Quantité 96 tests
Fiche technique Fiche technique

OPA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313400
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313399
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094365
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits OPA1

Ruegsegger, Manjunatha, Summer, Gopala, Zabeilski, Dasari, Vanderboom, Lanza, Klaus, Nair: "Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 3, pp. 4458-4472, (2019) (PubMed).

Chang, Chang, Wu, Cheng, Lin, Chang, Kuo, Chen, Liu: "Mitochondrial transplantation regulates antitumour activity, chemoresistance and mitochondrial dynamics in breast cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 30, (2019) (PubMed).

Du, Wen, Wang, Karmaus, Khatamian, Tan, Li, Guy, Nguyen, Dhungana, Neale, Peng, Yu, Chi: "Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells." dans: Nature, Vol. 558, Issue 7708, pp. 141-145, (2018) (PubMed).

Shao, Zhao, Wang, Liu, Zong, Xing: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." dans: Biological trace element research, (2018) (PubMed).

Nobis, Goichon, Achamrah, Guérin, Azhar, Chan, Morin, Bôle-Feysot, do Rego, Vaudry, Déchelotte, Belmonte, Coëffier: "Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia." dans: Scientific reports, Vol. 8, Issue 1, pp. 7233, (2018) (PubMed).

Chen, Chan, Linnane, Mao, Anwer, Sapkota, Annissa, Herok, Vissel, Oliver, Saad, Gorrie: "L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury." dans: Scientific reports, Vol. 8, Issue 1, pp. 11201, (2018) (PubMed).

Chan, Saad, Al-Odat, Oliver, Pollock, Jones, Chen: "Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers." dans: Frontiers in molecular neuroscience, Vol. 10, pp. 33, (2017) (PubMed).

Hui, Lu, Han, Zhou, Liu, Li, Jin: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." dans: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).

Tan, Toops, Lakkaraju: "Protective responses to sublytic complement in the retinal pigment epithelium." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 31, pp. 8789-94, (2016) (PubMed).

Ku, Ji, Zhang, Li, Sang: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." dans: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à OPA1

OPA1, mitochondrial dynamin like GTPase (Opa1), OPA1, mitochondrial dynamin like GTPase (OPA1), optic atrophy 1 (autosomal dominant) (opa1), 1200011N24Rik, AI225888, AI847218, fk62d06, largeG, lilr3, MGM1, mKIAA0567, NPG, NTG, wu:fb77a10, wu:fk62d06, zgc:92092

Protein level used designations for OPA1

  • dynamin-like 120 kDa protein, mitochondrial
  • large GTP-binding protein
  • largeG
  • optic atrophy 1 homolog
  • optic atrophy protein 1 homolog
  • RN protein
  • optic atrophy 1 (autosomal dominant)
  • optic atrophy 1-like protein
  • dynamin-like guanosine triphosphatase
  • mitochondrial dynamin-like GTPase
  • optic atrophy protein 1
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