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OPCML Produits

(Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Catégories

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories OPCML en vedette

OPCML Anticorps

High quality antibodies with extensive validation data.

OPCML Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

OPCML recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN540584
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN1881594
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN6263790
Quantité 100 μL
Fiche technique Fiche technique

OPCML recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4884030
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6386192
Quantité 96 tests
Fiche technique Fiche technique

OPCML recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313406
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7320058
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7320095
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits OPCML

Birtley, Alomary, Zanini, Antony, Maben, Weaver, Von Arx, Mura, Marinho, Lu, Morecroft, Karali, Chayen, Tate, Jurewicz, Stern, Recchi, Gabra: "Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions." dans: Nature communications, Vol. 10, Issue 1, pp. 3134, (2019) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Wang, Zhu, Song, Chen, Chen: "Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cancer patients using laser microdissection and cDNA microarray." dans: World journal of gastroenterology, Vol. 12, Issue 43, pp. 6949-54, (2006) (PubMed).

Sellar, Watt, Rabiasz, Stronach, Li, Miller, Massie, Miller, Contreras-Moreira, Scott, Brown, Williams, Bates, Smyth, Gabra: "OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer." dans: Nature genetics, Vol. 34, Issue 3, pp. 337-43, (2003) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." dans: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à OPCML

opioid binding protein/cell adhesion molecule like (OPCML), opioid binding protein/cell adhesion molecule-like (Opcml), 2900075O15Rik, 3732419F12, AI844366, B930023M13Rik, C230027C17, Gm181, IGLON1, OBCAM, Obcam, OPCM

Protein level used designations for OPCML

  • IgLON family member 1
  • opioid binding protein/cell adhesion molecule-like preprotein
  • opioid-binding protein/cell adhesion molecule
  • opioid binding cell adhesion molecule
  • OBCAM
  • opioid-binding cell adhesion molecule
  • opioid-binding protein/cell adhesion molecule-like
  • OBCAM alpha 1 isoform
  • OBCAM protein gamma isoform
  • neurite inhibitor GP55-A
  • opioid-binding protein/cell adhesion molecule homolog
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