Osteopontin Protéines
(Secreted phosphoprotein 1 (SPP1))
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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SPP1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by HPLC
SPP1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 87 % by SDS-PAGE.
Active
SPP1
Origine: Cynomolgus
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Active
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>95 % , as determined by SDS-PAGE and HPLC
Active
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>95 % , as determined by SDS-PAGE and HPLC
Active
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, AcA
Active
SPP1
Origine: Rat
Hôte: HEK-293 Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
SPP1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
SPP1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 85 % as determined by SDS-PAGE.
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 85 % as determined by SDS-PAGE.
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 85 % as determined by SDS-PAGE.
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Native
> 95 % pure
ELISA, LETIA
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
> 95 %
AcA, CC
Active
2 images
SPP1
Origine: Rat
Hôte: HEK-293 Cells
> 95 %
AcA, CC
Active
2 images
SPP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
90 %
ELISA
1 image
3 références
SPP1
Origine: Humain
Hôte: Insect cells (Sf9)
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SPP1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Dernières publications pour nos Osteopontin Protéines
: "Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 1, pp. 426-30, (1992) (PubMed).
: "cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)." dans: Genomics, Vol. 7, Issue 4, pp. 491-502, (1990) (PubMed).
: "The cDNA and derived amino acid sequence for human osteopontin." dans: Nucleic acids research, Vol. 17, Issue 8, pp. 3306, (1989) (PubMed).
: "cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)." dans: Genomics, Vol. 7, Issue 4, pp. 491-502, (1990) (PubMed).
: "The cDNA and derived amino acid sequence for human osteopontin." dans: Nucleic acids research, Vol. 17, Issue 8, pp. 3306, (1989) (PubMed).
Pseudonymes pour Osteopontin Protéines
secreted phosphoprotein 1 (SPP1) Protéinessecreted phosphoprotein 1 (Spp1) Protéines
secreted phosphoprotein 1 (spp1) Protéines
2AR Protéines
Apl-1 Protéines
BNSP Protéines
Bsp Protéines
BSPI Protéines
Eta Protéines
ETA-1 Protéines
OP Protéines
OPN Protéines
Opn Protéines
Opnl Protéines
OSP Protéines
Ric Protéines
Spp-1 Protéines
zgc:111821 Protéines
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