PAI1 Protéines
(Plasminogen Activator Inhibitor 1 (SERPINE1))
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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39 Résultats
SERPINE1
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
SERPINE1
Origine: Souris
Hôte: Human Cells
Recombinant
> 95 % as determined by SDS-PAGE
1 image
SERPINE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
SERPINE1
Origine: Porc
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
SERPINE1
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
SERPINE1
Origine: Humain
Hôte: Mammalian Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
SERPINE1
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINE1
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINE1
Origine: Rat
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SERPINE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
SERPINE1
Origine: Boeuf (Vache)
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
SERPINE1
Origine: Souris
Hôte: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
WB, ELISA
SERPINE1
Origine: Singe
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
SERPINE1
Origine: Souris
Hôte: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINE1
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
SERPINE1
Origine: Macaque rhésus
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
SERPINE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
SERPINE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
Dernières publications pour nos PAI1 Protéines
: "Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects." dans: PLoS ONE, Vol. 10, Issue 2, pp. e0116883, (2015) (PubMed).: "Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits." dans: American journal of respiratory cell and molecular biology, Vol. 52, Issue 4, pp. 429-37, (2015) (PubMed).
: "Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation." dans: Blood, Vol. 125, Issue 8, pp. 1339-48, (2015) (PubMed).
: "A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage." dans: Cellular signalling, Vol. 27, Issue 5, pp. 923-33, (2015) (PubMed).
: "Anti-tissue plasminogen activator (tPA) as an effective therapy of neonatal hypoxia-ischemia with and without inflammation." dans: CNS neuroscience & therapeutics, Vol. 21, Issue 4, pp. 367-73, (2015) (PubMed).
: "The time course of resolution of adhesions during fibrinolyitic therapy in tetracycline-induced pleural injury in rabbits." dans: American journal of physiology. Lung cellular and molecular physiology, pp. ajplung.00136.2015, (2015) (PubMed).
: "Inhibition of PAI-1 antiproteolytic activity against tPA by RNA aptamers." dans: Nucleic acid therapeutics, Vol. 24, Issue 4, pp. 239-49, (2014) (PubMed).
: "SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence." dans: Aging cell, Vol. 13, Issue 5, pp. 890-9, (2014) (PubMed).
: "Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex." dans: Biochemistry, Vol. 52, Issue 27, pp. 4697-709, (2013) (PubMed).
: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).
Pseudonymes pour PAI1 Protéines
serpin family E member 1 (SERPINE1) Protéinesserpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog (serpine1.L) Protéines
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (serpine1) Protéines
serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1) Protéines
serpin family E member 1 (Serpine1) Protéines
PAI Protéines
PAI-1 Protéines
PAI1 Protéines
Pai1 Protéines
PAI1A Protéines
Pai1aa Protéines
Planh Protéines
PLANH1 Protéines
Planh1 Protéines
RATPAI1A Protéines
SERPINE1 Protéines
si:ch211-138a11.1 Protéines
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