PAI1 Protein (AA 24-402) (His tag)

N° du produit ABIN1691566

Détail du produit

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Type de proteíne: Recombinant

Attributs du protein: AA 24-402

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette PAI1 protéine est marqué à la His tag.

Fonction: Recombinant Mouse Plasminogen Activator Inhibitor 1/PAI-1/SERPIN E1 (C-6His)

Séquence: LPLRESHTAH QATDFGVKVF QQVVQASKDR NVVFSPYGVS SVLAMLQMTT AGKTRRQIQD AMGFKVNEKG TAHALRQLSK ELMGPWNKNE ISTADAIFVQ RDLELVQGFM PHFFKLFQTM VKQVDFSEVE RARFIINDWV ERHTKGMISD LLAKGAVDEL TRLVLVNALY FSGQWKTPFL EASTHQRLFH KSDGSTVSVP MMAQSNKFNY TEFTTPDGLE YDVVELPYQG DTLSMFIAAP FEKDVHLSAL TNILDAELIR QWKGNMTRLP RLLILPKFSL ETEVDLRGPL EKLGMPDMFS ATLADFTSLS DQEQLSVAQA LQKVRIEVNE SGTVASSSTA FVISARMAPT EMVIDRSFLF VVRHNPTETI LFMGQVMEPV DHHHHHH

Attributs du produit: Recombinant Mouse Plasminogen activator inhibitor 1/SERPIN E1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu24-Ser402) of Mouse SERPIN E1 fused with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 5 months

Détail du antigène

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Autre désignation: SERPIN E1 (SERPINE1 Produits)

Synonymes: PAI Protein, PAI-1 Protein, PAI1 Protein, PLANH1 Protein, SERPINE1 Protein, si:ch211-138a11.1 Protein, Planh1 Protein, PAI1A Protein, Pai1 Protein, Pai1aa Protein, Planh Protein, RATPAI1A Protein, serpin family E member 1 Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Protein, serine (or cysteine) peptidase inhibitor, clade E, member 1 Protein, SERPINE1 Protein, serpine1.L Protein, serpine1 Protein, Serpine1 Protein

Sub Type: Fusionprotein

Sujet: Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
Alternative Names: Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1, Mr1, Pai1, Planh1,

Poids moléculaire: 43.7 kDa

UniProt: P22777

Pathways: Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration