p53 Protéines
(Tumor Protein P53 (TP53))
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| p53 Protein (AA 1-393) (GST tag) | Humain | Wheat germ |
|
624,00 €
Voir le prix
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| p53 Protein (AA 1-391) (His tag) | Rat | Escherichia coli (E. coli) |
|
532,31 €
Voir le prix
|
|
| p53 Protein (AA 1-393, full length) (His tag) | Humain | Mammalian Cells |
|
492,80 €
Voir le prix
|
|
| p53 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | Humain | HEK-293 Cells |
|
1.077,31 €
Voir le prix
|
|
| p53 Protein (AA 1-393) (His tag) | Humain | Escherichia coli (E. coli) |
|
230,69 €
Voir le prix
|
|
| p53 Protein (AA 1-393) (Strep Tag) | Humain | Cell-free protein synthesis (CFPS) |
|
à partir de 15.754,29 €
Voir le prix
|
|
| p53 Protein (AA 25-305, Tetramer) (His-Avi Tag,PE,p53) | Humain | HEK-293 Cells |
|
1.101,70 €
Voir le prix
|
|
| p53 Protein (AA 1-393, R273C) (His tag) | Humain | Escherichia coli (E. coli) |
|
523,08 €
Voir le prix
|
|
| p53 Protein (AA 7-393) (His-GFP tag Tag) | Humain | Escherichia coli (E. coli) |
|
615,38 €
Voir le prix
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| p53 Protein (AA 7-393) (His tag) | Humain | Escherichia coli (E. coli) |
|
476,92 €
Voir le prix
|
|
| p53 Protein (GST tag) | Humain | Baculovirus infected Insect Cells |
|
1.491,69 €
Voir le prix
|
|
| p53 Protein (GST tag) | Humain | Escherichia coli (E. coli) |
|
1.168,62 €
Voir le prix
|
|
| p53 Protéine | Humain | Escherichia coli (E. coli) |
|
1.119,79 €
Voir le prix
|
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| p53 Protein (AA 108-370) (His tag) | Humain | Escherichia coli (E. coli) |
|
870,52 €
Voir le prix
|
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| p53 Protein (AA 1-393) (His tag) | Humain | Escherichia coli (E. coli) |
|
870,52 €
Voir le prix
|
|
| p53 Protein (AA 90-354) (His tag) | Rat | Escherichia coli (E. coli) |
|
809,48 €
Voir le prix
|
|
| p53 Protein (AA 1-390) (His tag) | Souris | Escherichia coli (E. coli) |
|
611,08 €
Voir le prix
|
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| p53 Protein (AA 133-393) (His tag) | Humain | Escherichia coli (E. coli) |
|
870,52 €
Voir le prix
|
|
| p53 Protein (AA 134-387) (His tag) | Souris | Escherichia coli (E. coli) |
|
840,00 €
Voir le prix
|
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| p53 Protein (AA 1-386) (His tag) | Boeuf (Vache) | Escherichia coli (E. coli) |
|
1.778,00 €
Voir le prix
|
Protein
- AP (Affinity Purification: Application indiquée)
- AA (Antibody Array: Application indiquée)
- ELISA (ELISA: Application indiquée)
- WB (Western Blotting: Application indiquée)
3 références - Origine
- Humain
- Hôte
- Wheat germ
- Type Proteine
- Recombinant
Protein
- WB (Western Blotting: Image de validation disponible)
- ELISA (ELISA: Application indiquée)
- Origine
- Rat
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- Origine
- Humain
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- Greater than 85 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: Image de validation disponible)
- AcA (Activity Assay: Image de validation disponible)
- AbP (Antibody Production: Application indiquée)
- STD (Standard: Application indiquée)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Classe de qualité
- custom-made
- Origine
- Humain
- Hôte
- Cell-free protein synthesis (CFPS)
- Type Proteine
- Recombinant
- Pureté
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Activité biologique
- Active
Protein
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- Baculovirus infected Insect Cells
- Type Proteine
- Recombinant
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 % pure
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 80 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Rat
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 97 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 80 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 97 %
Protein
- Imm (Immunogen: Application indiquée)
- Origine
- Boeuf (Vache)
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
Dernières publications pour nos p53 Protéines
: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." dans: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).
: "Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse." dans: Scientific reports, Vol. 6, pp. 26187, (2016) (PubMed).
: "A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems." dans: Journal of molecular biology, Vol. 428, Issue 20, pp. 4154-4167, (2016) (PubMed).
: "LC-MS/MS-based targeted proteomics quantitatively detects the interaction between p53 and MDM2 in breast cancer." dans: Journal of proteomics, Vol. 152, pp. 172-180, (2016) (PubMed).
: "A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 23, Issue 9, pp. 1834-42, (2014) (PubMed).
: "Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance." dans: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 12, pp. 2367-79, (2012) (PubMed).
: "Characterization of the human p53 gene." dans: Molecular and cellular biology, Vol. 6, Issue 5, pp. 1379-85, (1987) (PubMed).
: "Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells." dans: The EMBO journal, Vol. 4, Issue 5, pp. 1251-5, (1985) (PubMed).
: "Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53." dans: Molecular and cellular biology, Vol. 5, Issue 7, pp. 1601-10, (1985) (PubMed).
: "Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse." dans: Scientific reports, Vol. 6, pp. 26187, (2016) (PubMed).
: "A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems." dans: Journal of molecular biology, Vol. 428, Issue 20, pp. 4154-4167, (2016) (PubMed).
: "LC-MS/MS-based targeted proteomics quantitatively detects the interaction between p53 and MDM2 in breast cancer." dans: Journal of proteomics, Vol. 152, pp. 172-180, (2016) (PubMed).
: "A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 23, Issue 9, pp. 1834-42, (2014) (PubMed).
: "Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance." dans: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 12, pp. 2367-79, (2012) (PubMed).
: "Characterization of the human p53 gene." dans: Molecular and cellular biology, Vol. 6, Issue 5, pp. 1379-85, (1987) (PubMed).
: "Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells." dans: The EMBO journal, Vol. 4, Issue 5, pp. 1251-5, (1985) (PubMed).
: "Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53." dans: Molecular and cellular biology, Vol. 5, Issue 7, pp. 1601-10, (1985) (PubMed).
Pseudonymes pour p53 Protéines
tumor protein p53 (TP53) Protéinescellular tumor antigen p53 (CpipJ_CPIJ002758) Protéines
tumor protein p53 (Tp53) Protéines
tumor protein p53 (tp53) Protéines
transformation related protein 53 (Trp53) Protéines
tumor protein p53 L homeolog (tp53.L) Protéines
bbl Protéines
BCC7 Protéines
bfy Protéines
bhy Protéines
brp53 Protéines
drp53 Protéines
etID22686.5 Protéines
fb40d06 Protéines
LFS1 Protéines
p44 Protéines
P53 Protéines
p53 Protéines
Tp53 Protéines
tp53 Protéines
TP53 Protéines
TRP53 Protéines
Trp53 Protéines
wu:fb40d06 Protéines
Xp53 Protéines
zgc:111919 Protéines
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