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PCSK5 Produits

(Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Catégories PCSK5 en vedette

PCSK5 Anticorps

High quality antibodies with extensive validation data.

PCSK5 Kits ELISA

Reliable ELISA kits for a wide range of species.

PCSK5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PCSK5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7435742
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (3)
N° du produit ABIN7164820
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN1881639
Quantité 400 μL
Fiche technique Fiche technique

PCSK5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958853
Quantité 96 tests
Fiche technique Fiche technique

PCSK5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1314358
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314359
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094407
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PCSK5

Heng, Dynon, Li, Edgell, Walton, Rombauts, Vollenhoven, Nie: "Development of a high-throughput assay for human proprotein convertase 5/6 for detecting uterine receptivity." dans: Analytical biochemistry, Vol. 475, pp. 14-21, (2015) (PubMed).

Harihar, Pounds, Iwakuma, Seidah, Welch: "Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing." dans: PLoS ONE, Vol. 9, Issue 1, pp. e84958, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Heng, Paule, Hardman, Li, Singh, Rainczuk, Stephens, Nie: "Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment." dans: Endocrinology, Vol. 151, Issue 8, pp. 3909-17, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Iatan, Dastani, Do, Weissglas-Volkov, Ruel, Lee, Huertas-Vazquez, Taskinen, Prat, Seidah, Pajukanta, Engert, Genest: "Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels." dans: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 467-75, (2009) (PubMed).

Szumska, Pieles, Essalmani, Bilski, Mesnard, Kaur, Franklyn, El Omari, Jefferis, Bentham, Taylor, Schneider, Arnold, Johnson, Tymowska-Lalanne, Stammers, Clarke, Neubauer, Morris, Brown, Shaw-Smith, Cama, Capra, Ragoussis, Constam, Seidah, Prat, Bhattacha: "VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5." dans: Genes & development, Vol. 22, Issue 11, pp. 1465-77, (2008) (PubMed).

Jin, Wang, Millar, Quertermous, Rothblat, Glick, Rader: "Hepatic proprotein convertases modulate HDL metabolism." dans: Cell metabolism, Vol. 6, Issue 2, pp. 129-36, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à PCSK5

proprotein convertase subtilisin/kexin type 5 (PCSK5), proprotein convertase subtilisin/kexin type 5 (Pcsk5), proprotein convertase subtilisin/kexin type 5 S homeolog (pcsk5.S), proprotein convertase subtilisin/kexin type 5 (LOC528098), proprotein convertase subtilisin/kexin type 5 (pcsk5), proprotein convertase subtilisin/kexin type 5b (pcsk5b), b2b585Clo, b2b1549Clo, fur2, MGC98915, PC5, Pc5, PC5/6A, PC5A, PC6, pc6, PC6A, PCSK5, pcsk5, SPC6, spc6, spc6A, spc6a, subtilase, zgc:165659

Protein level used designations for PCSK5

  • hPC6
  • prohormone convertase 5
  • proprotein convertase 6
  • protease PC6
  • subtilisin/kexin-like protease PC5
  • proprotein convertase 5
  • proprotein convertase PC5
  • subtilisin-like proprotein convertase 6
  • proprotein convertase subtilisin/kexin type 5
  • proprotein convertase PC6
  • proprotein convertase 6A
  • proprotein convertase 6B
  • proprotein convertase 6C
  • proprotein convertase 6D
  • proprotein convertase 6E
  • proprotein convertase 6F
  • subtilisin-like protease SPC6A
  • pc5.2
  • pcsk5.2
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