PCSK5 anticorps (N-Term)

N° du produit ABIN1881639

Détail du produit anti-PCSK5 anticorps

Antigène: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Épitope: AA 95-124, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCSK5 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PCSK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the N-terminal region of human PCSK5.

Clone: RB41935

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PCSK5 (ABIN1881639)

Heng, Paule, Hardman, Li, Singh, Rainczuk, Stephens, Nie: "Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment." dans: Endocrinology, Vol. 151, Issue 8, pp. 3909-17, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Iatan, Dastani, Do, Weissglas-Volkov, Ruel, Lee, Huertas-Vazquez, Taskinen, Prat, Seidah, Pajukanta, Engert, Genest: "Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels." dans: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 467-75, (2009) (PubMed).

Détails sur PCSK5

Antigène: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Autre désignation: PCSK5 (PCSK5 Produits)

Synonymes: anticorps PC5, anticorps PC6, anticorps PC6A, anticorps SPC6, anticorps subtilase, anticorps PC5/6A, anticorps PC5A, anticorps b2b1549Clo, anticorps b2b585Clo, anticorps Pc5, anticorps fur2, anticorps spc6, anticorps spc6A, anticorps MGC98915, anticorps PCSK5, anticorps pc6, anticorps spc6a, anticorps pcsk5, anticorps zgc:165659, anticorps proprotein convertase subtilisin/kexin type 5, anticorps proprotein convertase subtilisin/kexin type 5 S homeolog, anticorps proprotein convertase subtilisin/kexin type 5b, anticorps PCSK5, anticorps Pcsk5, anticorps pcsk5.S, anticorps LOC528098, anticorps pcsk5, anticorps pcsk5b

Sujet: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 206942

NCBI Accession: NP_001177411, NP_006191

UniProt: Q92824

Pathways: Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones