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PD-1 Produits

(Programmed Cell Death 1 (PDCD1))

Catégories

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008].

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Catégories PD-1 en vedette

PD-1 Anticorps

High quality antibodies with extensive validation data.

PD-1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PD-1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PD-1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (2)
  • (3)
  • (1)
N° du produit ABIN735608
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (8)
N° du produit ABIN7440431
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application FACS, WB, ELISA
Validations
  • (5)
N° du produit ABIN7193524
Quantité 0.1 mg
Fiche technique Fiche technique

PD-1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958801
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
N° du produit ABIN6971295
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969576
Quantité 96 tests
Fiche technique Fiche technique

PD-1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
N° du produit ABIN7275419
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
N° du produit ABIN7275418
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7275420
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PD-1

Assi, Wong, Tipton, Mei, Wong, Razo, Chan, Howng, Sagert, Krimm, Diep, Jang, Nguyen, Lapuyade, Singson, Villanueva, Paidhungat, Liu, Rangan, Vasiljeva, West, Richardson, Irving, Daniel, Belvin et al.: "Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents. ..." dans: Cancer immunology research, Vol. 9, Issue 12, pp. 1451-1464, (2022) (PubMed).

Curnock, Bossi, Kumaran, Bawden, Figueiredo, Tawar, Wiseman, Henderson, Hoong, Gonzalez, Ghadbane, Knight, ODwyer, Overton, Lucato, Smith, Reis, Page, Whaley, McCully, Hearty, Mahon, Weber: "Cell-targeted PD-1 agonists that mimic PD-L1 are potent T cell inhibitors." dans: JCI insight, Vol. 6, Issue 20, (2021) (PubMed).

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." dans: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Wang, Kang, Chen, Jehng, Jones, Chen, Huang, Chen: "An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses." dans: Nature communications, Vol. 11, Issue 1, pp. 1395, (2020) (PubMed).

Fan, Tian, Chen, Liu, Zhou, He, Coleman, Dong, Li, Huang, Xu, Zhang, Gao, Zhou, Ding, Chen: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." dans: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).

Wang, Ni, Zhou, He, Gao, Wu, Wu, Wu, Qiu, Zhou, Chen, Pan, Huang, Li, Bian, Yang, Miao, Liu: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." dans: Cancer immunology, immunotherapy : CII, (2020) (PubMed).

Tagawa, Kurashima, Takagi, Maekawa, Konnai, Shimbo, Matsumoto, Inokuma, Kawamoto, Miyahara: "Evaluation of costimulatory molecules in dogs with B cell high grade lymphoma." dans: PLoS ONE, Vol. 13, Issue 7, pp. e0201222, (2019) (PubMed).

Panda, Mehnert, Hirshfield, Riedlinger, Damare, Saunders, Kane, Sokol, Stein, Poplin, Rodriguez-Rodriguez, Silk, Aisner, Chan, Malhotra, Frankel, Kaufman, Ali, Ross, White, Bhanot, Ganesan: "Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer." dans: Journal of the National Cancer Institute, Vol. 110, Issue 3, pp. 316-320, (2019) (PubMed).

Li, Folkvord, Kovacs, Wagstaff, Mwakalundwa, Rendahl, Rakasz, Connick, Skinner: "Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection." dans: PLoS pathogens, Vol. 15, Issue 3, pp. e1007311, (2019) (PubMed).

Li, Song, Wang, Yin, Li, Lin, Meng, Feng, Jing: "Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion." dans: Oncogenesis, Vol. 8, Issue 3, pp. 17, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à PD-1

programmed cell death 1 (PDCD1), programmed cell death 1 (Pdcd1), CD279, hPD-1, hPD-l, Ly101, PD-1, PD1, Pdc1, SLEB2

Protein level used designations for PD-1

  • programmed cell death protein 1
  • protein PD-1
  • programmed cell death 1
  • programmed death 1
  • mPD-1
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