PD-L1 Protéines
(CD274 (PD-L1))
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
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81 Résultats
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Origine: Cynomolgus, Macaque rhésus
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
PD-L1
Origine: Cynomolgus
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Origine: Cynomolgus, Macaque rhésus
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
3 références
PD-L1
Origine: Humain
Hôte: HEK-293T Cells
Recombinant
WB, SDS, ELISA, PI
2 images
PD-L1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
1 reference
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
PD-L1
Origine: Souris
Hôte: Human Cells
Recombinant
> 95 % as determined by SDS-PAGE
1 image
PD-L1
Origine: Rat
Hôte: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
1 image
PD-L1
Origine: Cynomolgus
Hôte: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
1 image
PD-L1
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
Active
1 image
PD-L1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
1 image
PD-L1
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
Dernières publications pour nos PD-L1 Protéines
: "Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model." dans: Pharmaceutics, Vol. 13, Issue 2, (2021) (PubMed).: "PD-L1 aptamer isolation via Modular-SELEX and its applications in cancer cell detection and tumor tissue section imaging." dans: The Analyst, Vol. 146, Issue 9, pp. 2910-2918, (2021) (PubMed).
: "Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors." dans: EMBO molecular medicine, Vol. 12, Issue 6, pp. e11571, (2020) (PubMed).
: "Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models." dans: Cancer research, Vol. 80, Issue 3, pp. 549-560, (2020) (PubMed).
: "Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer. ..." dans: Nature medicine, Vol. 26, Issue 5, pp. 732-740, (2020) (PubMed).
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." dans: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "In Vitro Assays to Study PD-1 Biology in Human T Cells." dans: Current protocols in immunology, Vol. 130, Issue 1, pp. e103, (2020) (PubMed).
: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." dans: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).
: "Enhanced Expression of PD-L1 on Microglia After Surgical Brain Injury Exerts Self-Protection from Inflammation and Promotes Neurological Repair." dans: Neurochemical research, Vol. 44, Issue 11, pp. 2470-2481, (2019) (PubMed).
: "A small-sized protein binder specific for human PD-1 effectively suppresses the tumour growth in tumour mouse model." dans: Journal of drug targeting, pp. 1-9, (2019) (PubMed).
Pseudonymes pour PD-L1 Protéines
CD274 molecule (CD274) ProtéinesCD274 antigen (Cd274) Protéines
programmed cell death 1 ligand 2 (PDCD1LG2) Protéines
CD274 molecule (Cd274) Protéines
A530045L16Rik Protéines
B7-H Protéines
B7H1 Protéines
B7h1 Protéines
PD-L1 Protéines
PDCD1L1 Protéines
Pdcd1l1 Protéines
PDCD1LG1 Protéines
Pdcd1lg1 Protéines
PDL1 Protéines
Pdl1 Protéines
RGD1566211 Protéines
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