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PDE4B Protéines

(phosphodiesterase 4B, cAMP-Specific (PDE4B))

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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PDE4B Protein (AA 1-736) (His tag)

custom-made PDE4B Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant PDE4B Protein, UniprotID Q07343

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N° du produit ABIN7554878

Détails

PDE4B Protein (AA 500-736) (His tag)

PDE4B Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 90 % WB, PC, SDS, Imm

N° du produit ABIN7414258

Détails

PDE4B Protein (AA 1-736) (Strep Tag)

custom-made PDE4B Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3094409