(serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1))
The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.[provided by RefSeq, Mar 2011].
Deng, Gui, Kim, Xie, Chen, Li, He, Chen, Chen, Luo, Lu, Xie, Churchill, Xu, Zhou, Wu, Yu, John, Hirayasu, Nguyen, Liu, Huang, Li, Deng, Tang, Sadek, Zhang, Huang, Zou, Chen, Zhu, Arase, Xia, Jiang et al.: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." dans: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).
Zhang, Dai, Neng, Zhang, Zhi, Fridberger, Shi: "Perivascular macrophage-like melanocyte responsiveness to acoustic trauma--a salient feature of strial barrier associated hearing loss." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 9, pp. 3730-40, (2013) (PubMed).
Pseudonymes pour PEDF Protéines
serpin family F member 1 (SERPINF1) Protéines serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1) Protéines serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog (serpinf1.L) Protéines serpin family F member 1 (Serpinf1) Protéines serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1) Protéines AI195227 Protéines Dmrs91 Protéines EPC-1 Protéines MGC82984 Protéines OI6 Protéines OI12 Protéines PEDF Protéines Pedf Protéines Pedfl Protéines Sdf3 Protéines SERPINF1 Protéines zgc:92072 Protéines