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PEG10 Produits

(Paternally Expressed 10 (PEG10))

Catégories

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010].

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Catégories PEG10 en vedette

PEG10 Anticorps

High quality antibodies with extensive validation data.

PEG10 Kits ELISA

Reliable ELISA kits for a wide range of species.

PEG10 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PEG10 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (6)
N° du produit ABIN1681320
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, ICC
Validations
  • (3)
  • (3)
N° du produit ABIN969348
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN524962
Quantité 50 μg
Fiche technique Fiche technique

PEG10 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969163
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6225627
Quantité 96 tests
Fiche technique Fiche technique

PEG10 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314640
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094526
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3135926
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PEG10

Rotinen, You, Yang, Coetzee, Reis-Sobreiro, Huang, Huang, Pan, Yáñez, Hazelett, Chu, Steadman, Morrissey, Nelson, Corey, Chung, Freedland, Di Vizio, Garraway, Murali, Knudsen, Freeman: "ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis." dans: Nature medicine, Vol. 24, Issue 12, pp. 1887-1898, (2019) (PubMed).

Uxa, Bernhart, Mages, Fischer, Kohler, Hoffmann, Stadler, Engeland, Müller: "DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation." dans: Nucleic acids research, Vol. 47, Issue 17, pp. 9087-9103, (2019) (PubMed).

Peng, Zhu, Yin, Zhang, Wei, Liu, Liu, Gao, Jiang, Miao: "PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 30, (2017) (PubMed).

Shyu, Lee, Lu, Chen, Chien, Chen, Lin, Tsou, Chen, Hsieh, Huang: "miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma." dans: Journal of translational medicine, Vol. 14, Issue 1, pp. 200, (2016) (PubMed).

Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: "uORFs, reinitiation and alternative translation start sites in human mRNAs." dans: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).

Wang, Xiao, Hu, Chen, Liu, Hu: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." dans: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).

Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." dans: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à PEG10

paternally expressed 10 (PEG10), paternally expressed 10 (Peg10), AA407948, EDR, Edr, HB-1, Mar2, Mart2, MEF3L, MyEF-3, RGAG3

Protein level used designations for PEG10

  • MEF3 like 1
  • MEF3-like protein 1
  • embryonal carcinoma differentiation regulated
  • embryonal carcinoma differentiation-regulated protein
  • mammalian retrotransposon-derived protein 2
  • myelin expression factor 3-like protein 1
  • paternally expressed gene 10 protein
  • retrotransposon gag domain containing 3
  • retrotransposon gag domain-containing protein 3
  • retrotransposon-derived gag-like polyprotein
  • retrotransposon-derived protein PEG10
  • ty3/Gypsy-like protein
  • MyEF-3 like
  • embryonal carcinoma differentiation regulated protein
  • myelin expression factor 3
  • paternally expressed 10
  • LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10
  • retrotransposon-derived protein PEG10-like
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