PEN2 Produits
(Presenilin Enhancer 2 Homolog (PSENEN))
Catégories
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq, Jul 2008].
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Catégories PEN2 en vedette
PEN2 Anticorps
High quality antibodies with extensive validation data.
PEN2 Kits ELISA
Reliable ELISA kits for a wide range of species.
PEN2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PEN2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (2)
N° du produit
ABIN1387540
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7139851
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN565943
Quantité
100 μg
Fiche technique
Fiche technique
PEN2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6231793
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Cow
Analytical Method
Validations
N° du produit
ABIN2870254
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN6200572
Quantité
96 tests
Fiche technique
Fiche technique
PEN2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316522
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3107691
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3128357
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PEN2
: "Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice." dans: Acta biochimica et biophysica Sinica, Vol. 47, Issue 4, pp. 258-66, (2015) (PubMed).: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." dans: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1." dans: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 7850-4, (2003) (PubMed).
: "Membrane topology of gamma-secretase component PEN-2." dans: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 20117-23, (2003) (PubMed).
: "The role of presenilin cofactors in the gamma-secretase complex." dans: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).
: "APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity." dans: Biochemical and biophysical research communications, Vol. 305, Issue 3, pp. 502-9, (2003) (PubMed).
: "aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation." dans: Developmental cell, Vol. 3, Issue 1, pp. 85-97, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à PEN2
presenilin enhancer gamma-secretase subunit (PSENEN), presenilin enhancer 2 (PEN2), presenilin enhancer 2 (Psenen), presenilin enhancer gamma secretase subunit (Psenen), Gamma-secretase subunit pen-2 (pen-2), presenilin enhancer (pen-2), presenilin enhancer gamma secretase subunit S homeolog (psenen.S), presenilin enhancer gamma secretase subunit (psenen), presenilin enhancer gamma-secretase subunit (Psenen), 1700023M09Rik, ACYPI006208, anon-AE003800.1, CG33198, Dmel\\CG33198, dPen-2, MSTP064, PEN-2, Pen-2, pen-2, PEN2, pen2, Psenen, psenen, RGD1312037, zgc:109727Protein level used designations for PEN2
- gamma-secretase subunit PEN-2
- hematopoietic stem/progenitor cells protein MDS033
- presenilin enhancer protein 2
- presenilin enhancer 2
- LRRGT00140 mRNA
- liver regeneration-related protein LRRGT00140
- CG33198-PA
- pen-2-PA
- presenilin enhancer 2 homolog
- presenilin enhancer gamma secretase subunit S homeolog
- Presenilin enhancer protein 2 homolog
- presenilin enhancer protein 2 homolog
Avez-vous cherché autre chose?
- PEMT
- PELP1
- PELO
- Pellino 3
- Pellino 1
- PELI2
- PELE
- PELB
- PELA
- Pejvakin
- PEG3
- PEG10
- PEG
- PEF1
- PEDF
- PECR
- PECI/ECI2
- PEBP4
- PEBP1
- PEBB
- Penicillin
- Penicillin G
- Penicillinase
- pepA
- PEPCK
- PEPD
- PEPPI
- Pepsin
- Pepsin A
- Pepsinogen A
- Peptidase B
- Peptidase E
- Peptide F
- Peptide Histidine-Methionine
- Peptide YY
- Peptide YY, 2 (Pseudogene)
- Peptidoglycan
- Peptidylarginine Deiminase
- Peptidylglycine alpha-Amidating Monooxygenase
- Peptidylprolyl Isomerase
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