Amyloid beta (Abeta) (AA 1-42) Peptide
Abeta
Reactivité: Humain
Hôte: Synthetic
N° du produit ABIN2017638
Aperçu rapide pour Amyloid beta (Abeta) (AA 1-42) Peptide (ABIN2017638)
Antigène
beta Amyloid (Abeta)
(Amyloid beta (Abeta))
Origine
Humain
Source
Synthetic
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Protein Region
- AA 1-42
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Séquence
- DAEFRHDSGY EVHHQKLVFF AEDVGSNKGA IIGLMVGGVV IA
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Specificité
- Formula: C203H311N55O60S1
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Attributs du produit
- This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the 'longer forms' of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.
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Pureté
- > 95 %
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Restrictions
- For Research Use only
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Reconstitution
- Insoluble in water, may be dissolved in any buffer of pH >9.
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Stock
- -20 °C
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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Poids moléculaire
- 4514.100 kDa
Antigène
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