RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide
Aperçu rapide pour RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide (ABIN2183415)
Antigène
Origine
Source
Application
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Protein Region
- N-Term
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Séquence
- MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RORC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Sujet
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RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.
Alias Symbols: NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Protein Size: 518 -
Poids moléculaire
- 58 kDa
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ID gène
- 6097
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NCBI Accession
- NM_005060, NP_005051
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UniProt
- Q6I9R9
Antigène
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