This is a synthetic peptide designed for use in combination with anti-RORC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
RORC
(RAR-Related Orphan Receptor C (RORC))
Synonymes
NR1F3 Peptide, RORG Peptide, RZR-GAMMA Peptide, RZRG Peptide, TOR Peptide, Nr1f3 Peptide, RORgamma Peptide, Thor Peptide, RAR related orphan receptor C Peptide, RAR-related orphan receptor C Peptide, RAR-related orphan receptor gamma Peptide, RORC Peptide, Rorc Peptide
Sujet
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.