Thioredoxin Interacting Protein (TXNIP) (N-Term) Peptide
TXNIP
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN2183818
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Thioredoxin Interacting Protein (TXNIP) (N-Term) Peptide (ABIN2183818)
Antigène
TXNIP
(Thioredoxin Interacting Protein (TXNIP))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Séquence
- QTSEYLRYED TLLLEDQPTG ENEMVIMRPG NKYEYKFGFE LPQGPLGTSF
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TXNIP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
-
Sujet
-
TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Protein Size: 391 -
Poids moléculaire
- 43 kDa
-
ID gène
- 10628
-
NCBI Accession
- XP_003960219
-
UniProt
- Q9H3M7
Antigène
-
Vous êtes ici:
