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Thioredoxin Interacting Protein (TXNIP) Peptide

TXNIP Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN937587
382,12 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 20 à 27 jours ouvrables

Aperçu rapide pour Thioredoxin Interacting Protein (TXNIP) Peptide (ABIN937587)

Antigène

TXNIP (Thioredoxin Interacting Protein (TXNIP))

Origine

Mammifères

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of TXNIP antibody,
    Alternative Names: TXNIP control peptide, TXNIP antibody Blocking Peptide, Anti-TXNIP Blocking Peptide, Thioredoxin Interacting Protein Blocking Peptide, EST01027 Blocking Peptide, HHCPA78 Blocking Peptide, THIF Blocking Peptide, VDUP1 Blocking Peptide
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    TXNIP (Thioredoxin Interacting Protein (TXNIP))

    Sujet

    TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.

    Poids moléculaire

    44 kDa
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