Thioredoxin Interacting Protein (TXNIP) Peptide
Aperçu rapide pour Thioredoxin Interacting Protein (TXNIP) Peptide (ABIN937587)
Antigène
Origine
Source
Application
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Type de proteíne
- Synthetic
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Séquence
- DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of TXNIP antibody,
Alternative Names: TXNIP control peptide, TXNIP antibody Blocking Peptide, Anti-TXNIP Blocking Peptide, Thioredoxin Interacting Protein Blocking Peptide, EST01027 Blocking Peptide, HHCPA78 Blocking Peptide, THIF Blocking Peptide, VDUP1 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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Sujet
- TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
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Poids moléculaire
- 44 kDa
Antigène
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