Metastasis Associated 1 (MTA1) (Middle Region) Peptide
MTA1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits MTA1
- MTA1 (Metastasis Associated 1 (MTA1))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- QADITDLLKE GEEDGRDQSR LETQVWEAHN PLTDKQIDQF LVVARSVGTF
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-MTA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Metastasis Associated 1 (MTA1) peptide
MTA1 Reactivité: Humain Hôte: Synthetic BP, Imm
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- MTA1 (Metastasis Associated 1 (MTA1))
- Synonymes
- Tex22 Peptide, metastasis associated 1 Peptide, metastasis associated 1 L homeolog Peptide, MTA1 Peptide, Mta1 Peptide, mta1.L Peptide
- Sujet
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This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
Protein Size: 430 - ID gène
- 9112
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