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Metastasis Associated 1 (MTA1) Peptide

MTA1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN980315
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 15 à 22 jours ouvrables

Aperçu rapide pour Metastasis Associated 1 (MTA1) Peptide (ABIN980315)

Antigène

MTA1 (Metastasis Associated 1 (MTA1))

Origine

Humain

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-MTA1 antibody (Catalog #: ARP37737_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    MTA1 (Metastasis Associated 1 (MTA1))

    Sujet

    MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.

    Protein Interaction Partner: BLOC1S1,ITGB3BP,MNAT1,BLOC1S1,CCNH,DDX18,DYNLL1,ESR1,GPR183,GRB2,HDAC1,HDAC2,HIF1A,ITGB3BP,MNAT1,RBBP4,SH3GLB1,TH1L,TP53,ATR,CCNH,CDK7,CHD4,ESR1,FOXP1,GPR183,HDAC1,HDAC2,HIF1A,MBD3L1,MNAT1,MTA1,MTA2,NAA10,RBBP4,RBBP7,SIN3A,TH1L,TP53

    Protein Size: 430

    Poids moléculaire

    47 kDa

    ID gène

    9112

    NCBI Accession

    NM_001203258
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