This is a synthetic peptide designed for use in combination with anti-RGS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
RGS1
(Regulator of G-Protein Signaling 1 (RGS1))
Synonymes
1R20 Peptide, BL34 Peptide, IER1 Peptide, IR20 Peptide, RGS1 Peptide, 1r20 Peptide, bl34 Peptide, ier1 Peptide, ir20 Peptide, regulator of G protein signaling 1 Peptide, regulator of G-protein signaling 1 Peptide, regulator of G-protein signaling 1 S homeolog Peptide, Regulator of G-protein signaling 1 Peptide, RGS1 Peptide, Rgs1 Peptide, rgs1.S Peptide, rgs1 Peptide
Sujet
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.