Regulator of G-Protein Signaling 1 (RGS1) (N-Term) Peptide
Aperçu rapide pour Regulator of G-Protein Signaling 1 (RGS1) (N-Term) Peptide (ABIN8110205)
Antigène
Origine
Source
Application
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Protein Region
- N-Term
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Fonction
- RGS1 Peptide - N-terminal region
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Séquence
- LKGTTHSLLD DKMQKRRPKT FGMDMKAYLR SMIPHLESGM KSSKSKDVLS
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-RGS1 Antibody (ARP74181_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
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Sujet
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Background Information: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alternative Symbols: RGS1,1R20,BL34,IER1,
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Poids moléculaire
- 22kDa
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ID gène
- 5996
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NCBI Accession
- NP_002913
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UniProt
- Q08116
Antigène
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