Single-Minded Homolog 2 (SIM2) (Middle Region) Peptide
SIM2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5514030
Aperçu rapide pour Single-Minded Homolog 2 (SIM2) (Middle Region) Peptide (ABIN5514030)
Antigène
SIM2
(Single-Minded Homolog 2 (SIM2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-SIM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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Sujet
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM2,BHLHE15,
Protein Size: 667 -
ID gène
- 6493
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UniProt
- Q14190
Antigène
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