Single-Minded Homolog 2 (SIM2) (Middle Region) Peptide
SIM2
Reactivité: Humain
Hôte: Synthetic
WB
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- Antigène Tous les produits SIM2
- SIM2 (Single-Minded Homolog 2 (SIM2))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Séquence
- SWRTALSTSQ ETRKLVKPKN TKMKTKLRTN PYPPQQYSSF QMDKLECGQL
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- SIM2 (Single-Minded Homolog 2 (SIM2))
- Synonymes
- Xsim2 Peptide, sim2-A Peptide, xSim Peptide, HMC13F06 Peptide, HMC29C01 Peptide, SIM Peptide, bHLHe15 Peptide, single-minded family bHLH transcription factor 2 S homeolog Peptide, single-minded family bHLH transcription factor 2 Peptide, single-minded homolog 2 (Drosophila) Peptide, sim2.S Peptide, sim2 Peptide, SIM2 Peptide, Sim2 Peptide
- Sujet
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM, bHLHe15, HMC13F06, HMC29C01
Protein Size: 167 - ID gène
- 6493
- NCBI Accession
- NM_005069, NP_005060
- UniProt
- Q14190
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