This is a synthetic peptide designed for use in combination with anti- ACE2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
ACE2
(Angiotensin I Converting Enzyme 2 (ACE2))
Synonymes
ACE1 Peptide, CD143 Peptide, DCP Peptide, DCP1 Peptide, ICH Peptide, MVCD3 Peptide, ACEH Peptide, 2010305L05Rik Peptide, zgc:92514 Peptide, angiotensin I converting enzyme Peptide, angiotensin I converting enzyme 2 Peptide, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Peptide, ACE Peptide, ACE2 Peptide, Ace2 Peptide, ace2 Peptide
Sujet
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.