A synthetic peptide for use as a blocking control in assays to test for specificity of ACE2 antibody, Alternative Names: ACE2 control peptide, ACE2 antibody Blocking Peptide, Anti-ACE2 Blocking Peptide, Angiotensin I Converting Enzyme Blocking Peptide, Peptidyl-Dipeptidase A 2 Blocking Peptide, ACEH Blocking Peptide, DKFZP434A014 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
ACE2
(Angiotensin I Converting Enzyme 2 (ACE2))
Synonymes
ACE1 Peptide, CD143 Peptide, DCP Peptide, DCP1 Peptide, ICH Peptide, MVCD3 Peptide, ACEH Peptide, 2010305L05Rik Peptide, zgc:92514 Peptide, angiotensin I converting enzyme Peptide, angiotensin I converting enzyme 2 Peptide, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Peptide, ACE Peptide, ACE2 Peptide, Ace2 Peptide, ace2 Peptide
Sujet
ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this geneuggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.