N° du produit ABIN7887246
264,00 €
Plus frais de livraison 40,00 € et TVA
Destination:
France
Envoi sous 8 à 9 jours ouvrables
Aperçu rapide pour alpha-conotoxin IMI Peptide (ABIN7887246)
Antigène
alpha-conotoxin IMI
Origine
Conus imperialis
Source
Synthetic
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Type de proteíne
- Synthetic
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Activité biologique
- Active
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Fonction
- α-Conotoxin ImI
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Séquence
- GCCSDPRCAW RC-NH2
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Specificité
- Toxin target: α3β2 and α7 nAChRs
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Pureté
- ≥99 % (HPLC)
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Biological Activity Comment
- α-Conotoxin ImI potently and specifically blocks mammalian neuronal nAChR (α3/β2 > α7 > α3/β4)1.
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alpha-conotoxin IMI peptide (Atto 590)
Reactivité: Conus imperialis Hôte: Synthetic FM, IF, LCI
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Indications d'application
- Antigen Preadsorption Control: 0.1 - 10 μM
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. The product is readily soluble in high-quality pure water at micromolar to millimolar concentrations (typically 100 μM to 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x the final working concentration. Divide the stock solution into small, single-use aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.
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Buffer
- Lyophilized from double distilled water (ddH2O). May contain residual trifluoroacetate (TFA).
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Conseil sur la manipulation
- Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture
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Stock
- -20 °C
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Stockage commentaire
- The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.
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- alpha-conotoxin IMI
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Sujet
- A potent antagonist of the neuronal α3β2 and α7 nicotinic acetylcholine receptors (nAChR)
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Poids moléculaire
- 1351 Da
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UniProt
- P50983
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Numéro CAS
- 156467-85-5
Antigène
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