Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (N-Term) Peptide
Aperçu rapide pour Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (N-Term) Peptide (ABIN8094272)
Antigène
Origine
Source
Application
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Protein Region
- N-Term
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Fonction
- GRK2 Peptide - N-terminal region
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Séquence
- PEPSIRSVMQ KYLEDRGEVT FEKIFSQKLG YLLFRDFCLN HLEEARPLVE
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-ADRBK1 Antibody(ARP51965_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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Sujet
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Background Information: This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.
Alternative Symbols: BARK1, ADRBK1, BETA-ARK1
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Poids moléculaire
- 79kDa
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ID gène
- 156
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NCBI Accession
- NP_001610
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UniProt
- P25098
Antigène
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