Heat Shock 22kDa Protein 8 (HSPB8) (Middle Region) Peptide
Aperçu rapide pour Heat Shock 22kDa Protein 8 (HSPB8) (Middle Region) Peptide (ABIN8102217)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Fonction
- HSPB8 Peptide - middle region
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Séquence
- PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-HSPB8 Antibody(ARP55036_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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Sujet
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Background Information: HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Alternative Symbols: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
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Poids moléculaire
- 21kDa
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ID gène
- 26353
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NCBI Accession
- NP_055180
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UniProt
- Q9UJY1
Antigène
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