Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (Middle Region) Peptide
Aperçu rapide pour Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (Middle Region) Peptide (ABIN8115483)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Fonction
- UCP3 Peptide - middle region
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Séquence
- CTTGAMAVTC AQPTDVVKVR FQASIHLGPS RSDRKYSGTM DAYRTIAREE
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti- UCP3 Antibody (ARP80687_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
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Sujet
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Background Information: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.
Alternative Symbols: SLC25A9
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Poids moléculaire
- 30 kDa
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ID gène
- 7352
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NCBI Accession
- NP_003347
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UniProt
- P55916
Antigène
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