Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Peptide
LDLRAP1
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN935977
Aperçu rapide pour Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Peptide (ABIN935977)
Antigène
LDLRAP1
(Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- WTDTRETLLE GMLFSLKYLG MTLVEQPKGE ELSAAAIKRI VATAKASGKK
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of LDLRAP1 antibody,
Alternative Names: LDLRAP1 control peptide, LDLRAP1 antibody Blocking Peptide, Anti-LDLRAP1 Blocking Peptide, Low Density Lipoprotein Receptor Adaptor Protein 1 Blocking Peptide, ARH Blocking Peptide, ARH1 Blocking Peptide, ARH2 Blocking Peptide, DKFZp586D0624 Blocking Peptide, FHCB1 Blocking Peptide, FHCB2 Blocking Peptide, MGC34705 Blocking Peptide, LDLRAP1, LDLRAP-1, LDLRAP 1, LDLRAP-1 Blocking Peptide, LDLRAP 1 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
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Sujet
- LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.
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Poids moléculaire
- 34 kDa
Antigène
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