TNF Receptor-Associated Factor 6 (TRAF6) Peptide
TRAF6
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN936268
Aperçu rapide pour TNF Receptor-Associated Factor 6 (TRAF6) Peptide (ABIN936268)
Antigène
TRAF6
(TNF Receptor-Associated Factor 6 (TRAF6))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- YVTFMHLEAL RQRTFIKDDT LLVRCEVSTR FDMGSLRREG FQPRSTDAGV
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of TRAF6 antibody,
Alternative Names: TRAF6 control peptide, TRAF6 antibody Blocking Peptide, Anti-TRAF6 Blocking Peptide, TNF receptor-associated factor 6 Blocking Peptide, MGC:3310 Blocking Peptide, RNF85 Blocking Peptide, TRAF6, TRAF-6, TRAF 6, TRAF-6 Blocking Peptide, TRAF 6 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
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Sujet
- TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.
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Poids moléculaire
- 59 kDa
Antigène
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