RE1-Silencing Transcription Factor (REST) Peptide
REST
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
-
- Antigène Tous les produits REST
- REST (RE1-Silencing Transcription Factor (REST))
- Type de proteíne
- Synthetic
- Origine
- Mammifères
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- ANMGMALTND MYDLHELSKA ELAAPQLIML ANVALTGEAS GSCCDYLVGE
- Attributs du produit
-
A synthetic peptide for use as a blocking control in assays to test for specificity of Rest antibody,
Alternative Names: Rest control peptide, Rest antibody Blocking Peptide, Anti-Rest Blocking Peptide, RE1-silencing transcription factor Blocking Peptide, 2610008J04Rik Blocking Peptide, AA407358 Blocking Peptide, MGC150099 Blocking Peptide, NRSF Blocking Peptide
-
-
- Indications d'application
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C long term.
-
- Antigène
- REST (RE1-Silencing Transcription Factor (REST))
- Synonymes
- NRSF Peptide, XBR Peptide, 2610008J04Rik Peptide, AA407358 Peptide, xbr Peptide, nrsf Peptide, rest Peptide, resta Peptide, REST Peptide, RE1 silencing transcription factor Peptide, RE1-silencing transcription factor Peptide, RE1-silencing transcription factor S homeolog Peptide, REST Peptide, Rest Peptide, rest.S Peptide, rest Peptide, LOC615792 Peptide
- Sujet
- Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
- Poids moléculaire
- 118 kDa
-
Vous êtes ici:
