RE1-Silencing Transcription Factor (REST) (Middle Region) Peptide
REST
Reactivité: Souris
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits REST
- REST (RE1-Silencing Transcription Factor (REST))
- Protein Region
- Middle Region
- Origine
- Souris
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- ANMGMALTND MYDLHELSKA ELAAPQLIML ANVALTGEAS GSCCDYLVGE
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Rest Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Antigène
- REST (RE1-Silencing Transcription Factor (REST))
- Synonymes
- NRSF Peptide, XBR Peptide, 2610008J04Rik Peptide, AA407358 Peptide, xbr Peptide, nrsf Peptide, rest Peptide, resta Peptide, REST Peptide, RE1 silencing transcription factor Peptide, RE1-silencing transcription factor Peptide, RE1-silencing transcription factor S homeolog Peptide, REST Peptide, Rest Peptide, rest.S Peptide, rest Peptide, LOC615792 Peptide
- Sujet
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Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Alias Symbols: 2610008J04Rik, AA407358, MGC150099, NRSF
Protein Size: 1082 - Poids moléculaire
- 118 kDa
- ID gène
- 19712
- NCBI Accession
- NM_011263, NP_035393
- UniProt
- Q8VIG1
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