A synthetic peptide for use as a blocking control in assays to test for specificity of NUMA1 antibody, Alternative Names: NUMA1 control peptide, NUMA1 antibody Blocking Peptide, Anti-NUMA1 Blocking Peptide, nuclear mitotic apparatus protein 1 Blocking Peptide, NUMA Blocking Peptide, NUMA1, NUMA-1, NUMA 1, NUMA-1 Blocking Peptide, NUMA 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
NUMA1
(Nuclear Mitotic Apparatus Protein 1 (NUMA1))
Synonymes
NUMA Peptide, 6720401E04Rik Peptide, AA764025 Peptide, AL022610 Peptide, AU014979 Peptide, NUMA1 Peptide, NuMA Peptide, SP-H Peptide, numa Peptide, numa1 Peptide, nuclear mitotic apparatus protein 1 Peptide, nuclear mitotic apparatus protein 1 S homeolog Peptide, NUMA1 Peptide, Numa1 Peptide, numa1 Peptide, numa1.S Peptide
Sujet
NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.