Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide
NUMA1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits NUMA1
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-NUMA1 antibody (Catalog #: ARP50532_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Antigène
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Synonymes
- NUMA Peptide, 6720401E04Rik Peptide, AA764025 Peptide, AL022610 Peptide, AU014979 Peptide, NUMA1 Peptide, NuMA Peptide, SP-H Peptide, numa Peptide, numa1 Peptide, nuclear mitotic apparatus protein 1 Peptide, nuclear mitotic apparatus protein 1 S homeolog Peptide, NUMA1 Peptide, Numa1 Peptide, numa1 Peptide, numa1.S Peptide
- Sujet
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NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.
Alias Symbols: NUMA
Protein Interaction Partner: GNAI1,GPSM2,ACTR1A,EPB41,EPB41L1,EPB41L2,GNAI1,GPSM2,NCOA6,PIM1,RAD21,SMC1A,TNKS,YEATS4,ACTR1A,EPB41,EPB41L1,EPB41L2,GPSM2,NCOA6,NPM1,PIM1,RPAP1,SMC1A,SMC3,TNKS,YEATS4
Protein Size: 2115 - Poids moléculaire
- 238 kDa
- ID gène
- 4926
- NCBI Accession
- NM_006185, NP_006176
- UniProt
- Q14980
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