A synthetic peptide for use as a blocking control in assays to test for specificity of Bnip3 l antibody, Alternative Names: Bnip3l control peptide, Bnip3l antibody Blocking Peptide, Anti-Bnip3l Blocking Peptide, BCL2/adenovirus E1B interacting protein 3-like Blocking Peptide, C86132 Blocking Peptide, D14Ertd719e Blocking Peptide, Nip3L Blocking Peptide, Nix Blocking Peptide, Bnip3l, Bnipl-3, Bnipl 3, Bnipl-3 Blocking Peptide, Bnipl 3 Blocking Peptide
BNIP3L
Reactivité: Humain
Hôte: Synthetic
BP, BI
Sodium azide
Indications d'application
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
BNIP3L/NIX (BNIP3L)
(BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
Synonymes
BNIP3a Peptide, NIX Peptide, NIP3 Peptide, Nix Peptide, Nip3 Peptide, C86132 Peptide, D14Ertd719e Peptide, Nip3L Peptide, bnip3l Peptide, nip3 Peptide, zgc:110478 Peptide, bnip3l2 Peptide, wu:fb52b03 Peptide, wu:fc02h04 Peptide, BCL2 interacting protein 3 like Peptide, BCL2 interacting protein 3 Peptide, BCL2/adenovirus E1B interacting protein 3 Peptide, BCL2/adenovirus E1B interacting protein 3-like Peptide, BCL2/adenovirus E1B interacting protein 3-like b Peptide, BCL2/adenovirus E1B interacting protein 3-like a Peptide, BNIP3L Peptide, BNIP3 Peptide, Bnip3l Peptide, Bnip3 Peptide, bnip3lb Peptide, bnip3la Peptide
Sujet
Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.