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Runt-Related Transcription Factor 2 (RUNX2) Peptide

RUNX2 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN937574

Aperçu rapide pour Runt-Related Transcription Factor 2 (RUNX2) Peptide (ABIN937574)

Antigène

RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Origine

Mammifères

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    DTATSDFCLW PSTLSKKSQA GASELGPFSD PRQFPSISSL TESRFSNPRM

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of RUNX2 antibody,
    Alternative Names: RUNX2 control peptide, RUNX2 antibody Blocking Peptide, Anti-RUNX2 Blocking Peptide, Runt-Related Transcription Factor 2 Blocking Peptide, RUNX2, RUNX-2, RUNX 2, RUNX-2 Blocking Peptide, RUNX 2 Blocking Peptide
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    Sujet

    RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.

    Poids moléculaire

    57 kDa
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