A synthetic peptide for use as a blocking control in assays to test for specificity of SFRS1 antibody, Alternative Names: SFRS1 control peptide, SFRS1 antibody Blocking Peptide, Anti-SFRS1 Blocking Peptide, Splicing Factor Arginine/Serine-Rich 1 Blocking Peptide, Splicing Factor 2 Alternate Splicing Factor Blocking Peptide, SFRS1, SFRS-1, SFRS 1, SFRS-1 Blocking Peptide, SFRS 1 Blocking Peptide
SFRS1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.