A synthetic peptide for use as a blocking control in assays to test for specificity of SFRS1 antibody, Alternative Names: SFRS1 control peptide, SFRS1 antibody Blocking Peptide, Anti-SFRS1 Blocking Peptide, Splicing Factor Arginine/Serine-Rich 1 Blocking Peptide, Splicing Factor 2 Alternate Splicing Factor Blocking Peptide, SFRS1, SFRS-1, SFRS 1, SFRS-1 Blocking Peptide, SFRS 1 Blocking Peptide
SFRS1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene.