A synthetic peptide for use as a blocking control in assays to test for specificity of CD8 A antibody, Alternative Names: CD8A control peptide, CD8A antibody Blocking Peptide, Anti-CD8A Blocking Peptide, CD8a molecule Blocking Peptide, CD8 Blocking Peptide, Leu2 Blocking Peptide, MAL Blocking Peptide, p32 Blocking Peptide, CD8A, CD-8A, CDA 8, CD-8A Blocking Peptide, CD 8A Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Sujet
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.