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CD8a Molecule (CD8A) (Middle Region) Peptide

CD8A Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN974701
  • Antigène Tous les produits CD8 alpha (CD8A)
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    GKRLGDTFVL TLSDFRRENE GYYFCSALSN SIMYFSHFVP VFLPAKPTTT
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CD8A Antibody(ARP59114_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Synonymes
    cd8 Peptide, LOC100136450 Peptide, BB154331 Peptide, Ly-2 Peptide, Ly-35 Peptide, Ly-B Peptide, Lyt-2 Peptide, zgc:136643 Peptide, CD8 Peptide, Leu2 Peptide, MAL Peptide, p32 Peptide, RHACD8-4 Peptide, CD8a molecule Peptide, uncharacterized LOC100125537 Peptide, CD8 alpha Peptide, CD8 antigen, alpha chain Peptide, T-cell surface glycoprotein CD8 alpha chain Peptide, Cd8a Peptide, LOC100125537 Peptide, LOC100136450 Peptide, CD8A Peptide, cd8a Peptide, LOC100126556 Peptide
    Sujet
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CD8, Leu2, MAL, p32

    Protein Interaction Partner: B2M,CD3D,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-E,HLA-G,LAT,LCK,LGALS1,PTPRC,SREK1,SRSF1,CD3D,CD59,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-G,PTPRC

    Protein Size: 235
    Poids moléculaire
    24 kDa
    ID gène
    925
    NCBI Accession
    NM_001145873, NP_001139345
    UniProt
    P01732
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