Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) Peptide
CHRNB2
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939815
382,12 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 20 à 27 jours ouvrables
Aperçu rapide pour Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) Peptide (ABIN939815)
Antigène
CHRNB2
(Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Type de proteíne
- Synthetic
-
Séquence
- KIEVKHFPFD QQNCTMKFRS WTYDRTEIDL VLKSEVASLD DFTPSGEWDI
-
Attributs du produit
-
A synthetic peptide for use as a blocking control in assays to test for specificity of CHRNB2 antibody,
Alternative Names: CHRNB2 control peptide, CHRNB2 antibody Blocking Peptide, Anti-CHRNB2 Blocking Peptide, Cholinergic Receptor Nicotinic Beta 2 Blocking Peptide
-
-
Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) peptide
CHRNB2 Reactivité: Humain, Boeuf (Vache), Chien, Souris, Porc, Rat Hôte: Synthetic BP, Imm
-
-
Indications d'application
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20 °C long term.
-
-
- CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))
-
Sujet
- Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy. Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
-
Poids moléculaire
- 57 kDa
Antigène
-
Vous êtes ici:
